Inhibition of compensatory renal growth in rats
نویسندگان
چکیده
منابع مشابه
Compensatory and obligatory renal growth in rats.
SILBER, SHERMAN, AND RICHARD L. MALVIN. Compensatory and obligatory renal growth in rats. Am. J. Physiol. 226(l) : 114-l 17. 1974.-Renal size and function were studied in three groups of rats in an attempt to gain information relating to the control of renal size. One group consisted of normal rats into which a third kidney was transplanted; a second group consisted of unilaterally nephrectomiz...
متن کاملCompensatory renal growth after unilateral ureteral obstruction.
Compensatory renal growth after unilateral ureteral obstruction. The accumulation of bulk renal protein, RNA and DNA was studied in mice during a 35-day period of accelerated renal growth in the kidney contralateral to that obstructed by acute ureteral ligation. Control mice were sham-operated and nonoperated. RNA was determined by the method of Monroe and Fleck, DNA after Ceriotti and protein ...
متن کاملMetabolic Response to Renal Compensatory Growth
Forty-eight hours after unilateral nephrectomy in young male Sprague-Dawley rats the concentrations of free methionine, alanine and tyrosine in renal cortical tissue were increased by 15-65 percent while the corresponding plasma concentrations decreased by 23-35 percent. The renal cortical concentrations of valine and leucine increased by 41 percent and 26 percent while plasma concentrations re...
متن کاملUltrastructural changes and nestin expression accompanying compensatory renal growth after unilateral nephrectomy in adult rats
BACKGROUND Several renal disorders affect the glomerular podocytes. Compensatory structural and functional changes have been observed in animals that have undergone unilateral renal ablation. These changes occur as a pliant response to quench the increased functional demand to maintain homeostasis of fluid and solutes. Nestin is an intermediate filament protein present in the glomerular podocyt...
متن کاملThe Role of Renal “Work” in Compensatory Kidney Growth
In a series of studies designed to test the role of renal "work" in compensatory kidney growth we examined the relationship between absolute sodium reabsorption-which constitutes the bulk of renal energy expenditure, and growth of the remaining kidney at various intervals after contralateral nephrectomy.The increase in weight of the remaining kidney preceded the rise in sodium reabsorption and ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1972
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1972.sp009957